conferences
22nd IFSCC Congress, Edinburgh 2002 The property of stimulating the growth of fibroblasts and other useful potentials of cyanobacteria after a heat shock. It is widely known that aging of the skin is caused externally by ultraviolet (UV) light and internally by reactive oxygen species (ROS) produced in the body. For anti-aging, it is an important challenge to prevent ROS from oxidizing living tissue of the body. Aging, in its course, would negatively affect the growth and functions of fibroblasts, causing dermal changes, which in turn cause wrinkles and laxity. Cosmetics are expected to protect the skin from such damaging oxidization more effectively.

Our research presented this time is to study the effectiveness of the crude extract of cyanobacteria before and after heat shock for comparison. The cyanobacterium, found in hot spring, is thermophilic. The sample of cyanobacteria after heat shock is to be prepared by exposing to a higher temperature than the normal culture setting. The result shows that the cyanobacterium extract has such anti-activation property as SOD (superoxide dismutase) activity and inhibition of lipid peroxide formation. On the other hand, it is also found that the cyanobacterium extract after heat shock has the property of stimulating the growth of fibroblasts as well as these two anti-activation properties and that the SOD activity of the cyanobacterium extract shows great heating-resistance.

Based on these results, it is assumed that the cyanobacterium extract be of effective use as an ingredient of anti-aging cosmetics, and we expect new products and applications to be developed with the use of cyanobacteria in the anti-aging field.




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